Immune Repertoire Sequencing Market

Immune Repertoire Sequencing Market to Reach US$ 186.9 Million by 2030


Reports and Insights has published a new report titled, “Immune Repertoire Sequencing Market: Opportunity Analysis and Future Assessment 2022-2030

The immune repertoire sequencing market is estimated to reach at a value of US$ 111.0 Mn by the end of 2022 and expected to reach at a value of US$ 186.9 Mn by 2030 with a significant CAGR of 6.7%

Immune repertoire can be perceived as the aggregate of T cell receptors and B cell receptors (also named immunoglobulin) that makes up the organism's adaptive immune system. The rapid progress and advances in next generation sequencing (NGS) have allowed the establishment of a new and robust technology named as immune repertoire sequencing. The immune repertoire sequencing helps for inquiring the complementary determining region of these receptors.

Immune repertoire sequencing has assisted in profiling the antigen-specific information within lymphocytes and has turned out to be essentially crucial to understand the body’s auto-defense mechanism opposed to foreign agents. It is important to note that the Immune repertoire sequencing has turned out to be an extremely helpful instrument to quantify the configuration of B or T cell antigen receptor repertoires in basic research, such as immune repertoire development, vaccination, and lymphocyte lineage tracking, as well as in several different clinical settings, such as hematopoietic stem cell transplant recovery monitoring, minimal residual disease (MRD) monitoring, and cancer patient prognosis.

Having said that, the early IR-seq experiments have observed high PCR and sequencing errors that restricted their capability to perform unerring repertoire diversity and abundance quantification. Nevertheless, the continuous research activities for the same has resulted in several successful advances and progress in the present times. In present, the immune repertoire sequencing is employed in the comprehensive range of applications such as cancer immunotherapy, biomarkers discovery, asthma and allergies, infectious diseases, research and much more. Attributing to which, the global immune repertoire sequencing market is projected to rise significantly over the coming years.

Key Takeaways from the Market Study

  • The immune repertoire sequencing market is estimated to reach at a value of US$ 111.0 Mn by the end of 2022 and expected to reach at a value of US$ 186.9 Mn by 2030 with a significant CAGR of 6.7%
  • The assay kits product segment in immune repertoire sequencing market is expected to create an incremental opportunity of US$ 25.6 Mn during the forecast period
  • In 2022, cancer immunotherapy application segment accounted for the largest market share and expected to grow at 7.9% CAGR during the forecast period.
  • In 2022, the diagnostics labs end user segment accounted for the largest market share
  • Asia Pacific region is expected to remain the prominent region in the global market and is estimated to remain the fastest growing region
  • The U.S. immune repertoire sequencing market is expected to increase 1.8X during the forecast period

Increasing usage of IR-seq in biomarker discovery

  • The immune repertoire sequencing majorly serves its utility in outlining T- and B-cell receptor repertoires in an individual, which has paved the way to a comprehensive reservoir of information on procured immunity opposed to several pathogens. It is believed that the next-generation immune repertoire sequencing has enabled several researchers across the world to make refined and advanced immuno-bioinformatics probes. It has stimulated fascination and interest amongst the research community and biopharmaceutical industries in the field of clinical development of vaccine design, antibody engineering, and cellular immunotherapy. It is important to have a better understanding of the immune repertoire with the emergence of immunotherapy and precision medicine, where treatments are being formulated that are custom-made to an individual for higher efficacy. There are several treatments in development and put to use that impact the immune system.
  • Assessing the immune repertoire is likely to help to anticipate therapeutic results and be employed to monitor the effects of treatment. Notably, the immune repertoire sequencing is majorly employed in biomarker discovery in order to improve the hit ratio and cost-efficiency of rational drug development. For example, in November 2017, the Center for Commercialization of Cancer Immunotherapy (C3i) began providing T cell receptor-beta sequencing services in its Biomarker and Diagnostic unit in Canada. In addition to that, there are several organizations seeking to look for outcomes with regard to biomarkers in the immune system, thereby projected to drive the market growth over the years.

Reports and Insights Study identifies some of the key participating players in Illumina, Inc., Pacific Biosciences of California, Inc, Agilent Technologies, Inc, Oxford Nanopore Technologies, Ltd, Qiagen N.V., ThermoFisher Scientific, F. Hoffmann-La Roche Ltd, Takara Bio, Inc, Bristol-Myers Squibb, Adaptive Biotechnologies, Archerdx, INC., Irepertoire, INC., CD Genomics, and BGI.

Immune Repertoire Sequencing Market Segmentation

The global Immune Repertoire Sequencing market is segmented on the basis of type, configuration, operation, application, end use, and region.

By Product

Assay Kits

TCR Kits

BCR Kits


TCR Analysis Solutions

BCR Analysis Solutions

TCR & BCR Analysis Solutions





Sequencing Services

Data Analysis Services

Pre-Sequencing Services

By Subject Type



By Application

Pharmagenomics Based Drug Recovery

Next Generation Sequencing

Polymerase Chain Reaction


Biomarker Discovery

Autoimmune Diseases

Cancer Immunotherapy

Infectious Disease Research

Asthma and Allergy Research

Vaccine Development

Immunodeficiency Identification


By End User

Diagnostic Labs

Pharmaceutical and Biotech Companies

Research Institutes


By Region

North America

Latin America


Asia Pacific

Middle East


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